雷竞技raybetAgilent Technologies Thought Leader Award Supports Dr. Paul Watkins, Hamner-UNC Institute for Drug Safety Sciences
SANTA CLARA, Calif., Jan. 21, 2014
雷竞技raybetAgilent Technologies Inc. (NYSE: A) today announced thatDr. Paul B. Watkins, international drug safety expert and director of theHamner-University of North Carolina Institute for Drug Safety Sciences, has received an 雷竞技raybetAgilent Thought Leader Award in recognition of his ongoing work developing integrated methods to predict drug-induced liver injury (DILI).
This award continues 雷竞技raybetAgilent's support of the research Hamner scientists are conducting on drug induced liver injury (Hamner, 2011）。Dr. Watkins' studies involve mouse genetic models, patients who have experienced or are experiencing DILI, and patient-specific liver culture models derived from stem cells.
"There is an industry-wide need for new predictive tools that will assess the safety of drug compounds much earlier in the drug-development process," said Dr. Watkins, who also chairs theU.S. Drug-Induced Liver Injury Network, funded by the National Institutes of Health. "By integrating a variety of preclinical biological research applications using genetic and genomic data, we hope to better anticipate and prevent patients' possible adverse reactions to bio-pharmaceutical treatment."
Using 雷竞技raybetAgilent's nuclear magnetic resonance technology, SurePrint G3 microarray platform, and otherintegrated biology technologies, Watkins and his team hope to further elucidate the causes of drug-induced liver injury.
"Patients' susceptibility to adverse reactions appears to involve genetic makeup but is also associated with non-genetic factors, such as age, nutrition and drug interactions," said Dr. Watkins. "We are excited about the progress we are making in understanding this problem, and I am honored to receive the 雷竞技raybetAgilent Thought Leader Award in support of our efforts."
"Drug-induced liver injury is a primary reason why some promising new drug candidates fail during clinical development and why other drugs are pulled off the market," said Dr. John Fjeldsted, 雷竞技raybetAgilent's senior director for LC/MS research and development and executive sponsor of this award.
"We are delighted with the excellent research that Hamner scientists have produced and are very pleased to now recognize Dr. Watkins as an 雷竞技raybetAgilent Thought Leader," he added. "We believe the results of pan-omic studies of drug induced liver damage will make a significant contribution to the understanding of metabolomic, proteomic and genetic associations and lead to more certain toxicity testing in multiple markets."
About the 雷竞技raybetAgilent Thought Leader Award
The 雷竞技raybetAgilent Thought Leader Award promotes fundamental scientific advances of influential thought leaders in the life sciences and chemical analysis industries. Information about previous award recipients is available at雷竞技raybetAgilent's Thought Leader Program网站。
About the Hamner Institutes for Health Sciences
The Hamner Institutes for Health Sciences is a non-profit translational biomedical research institute located on an open, multidisciplinary campus in North Carolina's Research Triangle Park. Building upon 35 years of research excellence in toxicology, Hamner scientists and medical professionals focus on drug and chemical safety in collaboration with academic, industry, and government partners. Novel technologies used at the Hamner include genomic and bioinformatics approaches for improving toxicity testing,in silicomodels for predictive toxicology,体外models that utilize human cells or cell lines to evaluate perturbations of cellular responses and in vivo models to elucidate genes that play a role in susceptibility to drug-induced toxicities.有关更多信息，请访问www.thehamner.org。
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雷竞技raybetAgilent Technologies Inc. (NYSE: A) is the world's premier measurement company and a technology leader in chemical analysis, life sciences, diagnostics, electronics and communications. The company's 20,600 employees serve customers in more than 100 countries. Agilent had revenues of $6.8 billion in fiscal 2013. Information about Agilent is available atwww.雷竞技raybetagilent.com。
On Sept. 19, 2013, 雷竞技raybetAgilent announced plans to separate into two publicly traded companies through a tax-free spinoff of its electronic measurement business. The new company is named Keysight Technologies, Inc. The separation is expected to be completed in early November 2014.
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